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You're Not Taking the Medication as Prescribed Inconsistent dosing is one of the most common- and most fixable- reasons for poor results with GLP-1 medications

But GLP-1 side effects such as nausea, GI discomfort, and fatigue may make the early weeks of treatment tougher than expected

GLP-1 medications generally aren't appropriate with: Personal/family history of medullary thyroid carcinoma (MTC) Multiple Endocrine Neoplasia type 2 (MEN 2) History of pancreatitis Severe gastroparesis or GI motility disorders Pregnancy, trying to conceive, or breastfeeding A history of eating disorders (requires careful evaluation) Josh reviews your full history at your consult to confirm treatment is safe for you

Another study published in Diabetes Care in 2019 examined the effects of semaglutide on blood pressure in individuals with obesity and without diabetes

a Univariate analysis using Wilcoxon test for paired data