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12 It therefore seems likely that activated mast cells are a driving force in propagating microenviromental inflammatory circuits, by recruiting other types of cells, perhaps the neutrophils, 13 and inducing proteolytic and cytokine activities in the local environment

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MOTS-c converges on AMPK, the cells energy sensor, and under metabolic stress relocates to the nucleus to help regulate gene expression [4]

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doi: 10.2174/1389450053174596