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We used PH rats induced with MCT because it is the most classical and widely used in vivo model for nearly 60 years due to its simplicity, reproducibility and low cost [42]

For researchers wishing to compare their preclinical results to clinical literature, these limitations are important to know: Robinson et al

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Los investigadores de Harvard especularon que el OTMA producido por la alta [ingesta de] colina en la dieta puede aumentar la inflamacin, y esto puede promover la progresin del cncer de prstata a la enfermedad letal