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Interestingly, Ox-LDPE-MPs showed greater inflammatory responses and intestinal damage compared to LDPE-MPs which was hypothesized to result from their easier cellular accumulation (Wang et al., 2023b)

94 Conversely, specific beneficial microbiota can promote antitumor immunity

HIF-1 and c-Myc regulate tumor lactic acid accumulation, which is transported via MCTs in the TME

Neuroreport 7, 921923.10.1097/00001756-199603220-00018 277 WurtmanR

Artesunate (ART), an artemisinin derivative, overcomes sunitinib resistance in renal cancer, with ferroptosis observed specifically in KTCTL-26 cells via ROS burst, metabolic rewiring, and p53 induction, suggesting p53 as a potential biomarker for ART responsiveness (235, 236)