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Anyway, this selective modulation of specific SCFAsparticularly the dose-responsive elevation of butyratesuggests a potential mechanism by which LEO may ameliorate diabetic metabolic dysregulation, given the established role of butyrate in promoting gut integrity and insulin sensitivity

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individuals with obesity also experience reductions in the numbers of small- and medium-sized LDL particles and the total cholesterol with GLP-1RA treatment [51]