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Biological roles of ornithine aminotransferase (OAT) in plant stress tolerance: present progress and future perspectives

During Listeria monocytogenes infection, LLO promotes mitochondrial membrane permeabilization, facilitating mtDNA release and subsequent activation of the cGAS-STING pathway ( Similarly, Salmonella enterica serovar Typhimurium infection induces mitochondrial stress and mtDNA release in murine macrophages, thereby activating the cGAS-STING-dependent type I IFN response (Xu et al., 2022)