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Works in tandem with Centella (which stimulates internal collagen production) for a dual-pathway collagen support system

Br J Dermatol (2014) 171(1):15561

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For Group A, a 3-step dose escalation regimen (Day 14: 0.06, Days 58: 0.12, Days 912: 0.16 and Days 1320: 0.2 mg, respectively) was chosen, Group B received 0.6 mg for 4 days, and 0.12 mg SAR425899 until Day 20

Administration is supervised, with dosing tailored conservatively to patient needs