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Moreover, GLPs impede microglial motility, prevent activation-associated morphological remodeling, and dampen phagocytic capacity ( In experimental spinal cord injury models, GLPs preserve myelin ultrastructure and enhance functional recovery through multimodal neuroprotective actions: they suppress neuronal and oligodendroglial apoptosisevidenced by reduced caspase-3 cleavageattenuate neuroinflammation via downregulation of TNF- and myeloperoxidase (MPO) activity, and counteract oxidative damage by decreasing MDA and NO levels while boosting SOD activity

The Central Role of the NAD+ Molecule in the Development of Aging and the Prevention of Chronic Age-Related Diseases: Strategies for NAD+ Modulation