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Moreover, PI3K-Akt signaling was significantly enriched at mid- and late phases of iHLO development, implying the expansion and functional maturation of the liver organoid, along with structural organization and functional integration of different cell types within the organoid

The rising incidence of obesity, sedentary lifestyles, and poor dietary choices are significant contributors to the growing rates of fatty liver disease

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We also closely monitor thyroid function in patients with existing thyroid disorders and assess the impact of renal impairment on treatment suitability