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Searches were performed in PubMed, ScienceDirect, and Google Scholar for publications between 1 January 2000 and 31 March 2025, using Boolean operators to combine terms such as (GLP-1 receptor agonist OR GLP-1 RA OR semaglutide OR liraglutide OR dulaglutide OR exenatide OR tirzepatide) AND (smoking cessation OR nicotine dependence OR nicotine addiction OR tobacco use disorder), as well as (GLP-1 receptor agonist OR GLP-1 RA) AND (weight gain OR obesity OR weight management OR post-cessation weight gain)