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5-fluorouracil enhances the antitumor activity of the glutaminase inhibitor cb-839 against pik3ca-mutant colorectal cancers

doi: 10.3389/fcell.2025.1596421 Received 19 March 2025 Accepted 22 April 2025 Published 13 May 2025 Volume 13 - 2025 Edited by Matteo Avella, Sidra Medicine, Qatar Reviewed by Jurandy Penitente-Filho, JPF Consultoria, Brazil Qi Yin, Carnegie Institution for Science, United States Updates Copyright 2025 Gmez-Elas, Luque, Oscoz-Susino, Novero, Briski, Ksparas, Steeman, Stival, Lavolpe, Julianelli, Geller, Attie, Vassena, Krapf and Buffone

Supporting Exercise Performance Exercise is a crucial component of weight loss

Instead of building a product narrative around abstract concepts such as beauty or luxury, brands increasingly focus on explaining the functional role of key ingredients

The activation of caspases in response to oxidative stress was closely linked to the observed reduction in aminophospholipid translocase activity and the increased PS externalization in aged RBCs