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3 In July 2018, the manufacturer removed albiglutide from the market due to financial reasons

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The three-way comparison between semaglutide, tirzepatide, and retatrutide consistently shows retatrutide at the top for total body weight percentage lost, and the difference becomes more pronounced at higher doses and longer treatment durations

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Slight increases in serum creatinine can occur during initial weight loss, but they usually reflect volume status changes, not actual kidney injury