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Saxenda represented the first time the FDA explicitly approved a GLP-1 compound for obesity treatment in non-diabetic patients, signaling regulatory recognition of weight loss benefits
G6PDH is a key enzyme in the OPPP, and it controls the amount of nicotinamide adenine dinucleotide phosphate (NADPH) by adjusting how glucose is processed in OPPP 120
That is the strongest class of evidence there is for a side effect: measured in randomized, controlled approval trials
British Thyroid Foundation
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