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In conclusion, PDHA1 modulates epigenetic modifications by increasing intracellular acetyl-CoA levels, which, in turn, enhances H3K27ac acetylation and promotes the expression of SLC7A11

The physiology of S-nitrosothiols: carrier molecules for nitric oxide

The initial conversion of tryptophan is catalyzed by IDO, the key rate-limiting enzyme in this pathway

Straka E, Ellinger I, Balthasar C, Scheinast M, Schatz J, Szattler T, Bleichert S, Saleh L, Knfler M, Zeisler H, Hengstschlger M, Rosner M, Salzer H, Gundacker C (2015) Mercury toxicokinetics of the healthy human term placenta involve amino acid transporters and ABC transporters