Last year, Johnson took a trip to a Latin American (i.e
resealing under dry, inert gas (e.g., nitrogen or argon) is sometimes used to reduce oxidation risk
Beyond biochemical activation, cellular interactions magnify thromboinflammation: activated platelets bind to NETs and to neutrophils via P-selectin/PSGL-1 and integrin pathways, forming plateletneutrophil aggregates that both promote further NET release and provide a nidus for coagulation complex assembly [66]
If neurological symptoms are present (such as paraesthesia, ataxia, cognitive changes, or visual disturbances), more intensive treatment is required
Abbreviations AMPK AMP-activated protein kinase COX II Cytochrome c oxidase subunit II mtDNA Mitochondrial DNA NEFA Nonesterified fatty acid PCR Polymerase chain reaction PGC-1 Peroxisome proliferator-activated receptor- coactivator-1 RPE Rating of perceived exertion VAS visual analogue scale Additional file Footnotes Competing interests This study was supported in part by a research fund from the KOHJIN Life Sciences Company, Ltd