Stabilization of an -helix by short adjacent accessory foldamers
They're dosing miscalculations that stem from confusion about peptide mass versus solution volume
The Substance works because the mechanism behind it is so stupid, so horribly disruptive, so physically disgusting and objectively sketchy, that it feels like something that would absolutely take root in our own culture, which despises fat people, and will do just about anything to get rid of them (or at least keep them in a state of perpetual shame for daring to exist)
This information, interpreted by a qualified provider, can support more informed conversation about which GLP-1 formulation may align with your biological profile
Still, gastroparesis is as awful as it is life-changing, and if semaglutide is causing it which it may very well be it should probably be on the label