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clinical presentation of high-risk (massive) poisoning Patients develop mitochondrial dysfunction very early (usually within 30 grams) may present with mental status alteration and lactic acidosis within 12 hours of ingestion

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JAMA - J Am Med Assoc 315(1):3646

An experimental GLP-1 pill helped people with obesity lose a significant amount of weight in a late-stage clinical trial, which suggests people who fear needles might soon have a way to take these medicines without the need for injections