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Alcohol dehydrogenase oxidizes ethanol with simultaneous formation of HO 2 , while the reaction catalyzed by microsomal enzymes generates the most dangerous OH (Bondy, 1992)

Establishment of comprehensive mechanistic models that incorporate mitochondrial oxidative stress, lipid metabolic reprogramming, and inflammatory amplification, to enable pathway-synergistic targeting

Subsequently, we treated BV2-simulated mouse microglia in a pathological activated state using OGD.Western blot analysis showed that Hv1 expression was weak in BV2 in the Sham group, whereas after OGD treatment, Hv1 expression was significantly enhanced

In CKD cats, oxidative stress can rise more easily

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