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Statins inhibit HMG-CoA reductase, decreasing ergosterol synthesis and impairing biofilms in Candida , Aspergillus , and zygomycetes, often synergizing with fluconazole (Macreadie et al., 2006

These patients also exhibit polymorphisms to the serotonin receptor 2A region of chromosome 13 and the human leukocyte antigen region of chromosome 6, as well as abnormalities in catechol- O -methyltransferase

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[PubMed] [Physiological Research] 43

On the other hand, patients with heart failure irrespective of LVEF were advised to receive SGLT2is, and those with atherosclerotic cardiovascular disease were advised to receive GLP1-RAs irrespective of their HbA1c levels