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The other critical consideration is muscle preservation

FDA encourages patients to talk with their healthcare provider or compounder about how to measure and administer the intended dose of compounded semaglutide, according to the agencys warning

Current evidence indicates that semaglutide treatment is associated with some degree of lean body mass reduction, though this occurs as part of overall weight loss rather than through a direct muscle-wasting mechanism

Dose of Mounjaro for Type 2 Diabetes (Adults and Children 10+) Initial dose: 2.5 mg subcutaneously once a week