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Rybelsus uses a SNAC (sodium N-[8-(2-hydroxybenzoyl) amino] caprylate) absorption enhancer that creates a localized pH change in the stomach, allowing semaglutide to cross the gastric mucosa

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Gene cloning KDX1, YHR033W, OSI1, ERC1 and FEX2 genes were cloned in pRS416TEF by PCR amplification followed by homologous recombination in yeast as described previously (Singh et al., 2024)

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