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9 Despite advancements in therapeutics, a healthy diet and exercise, with a reduction in overall caloric intake and reduced consumption of high-fat, high-fructose, and highly processed foods remain the most effective weapons in the fight against insulin resistance and diabetes

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Additionally, the drugs have been called anti-obesity medications (AOMs) by some researchers who criticize the drugs for the possibility of severe side effects, the lack of research into long-term use and the possibility of triggering eating disorders in some patients

According to KFF surgery data, about 1 in 8 individuals in the United States has used GLP-1 medications during their life and currently, approximately 15 million adults (or 6% of the population) are using prescription drugs for weight loss, type 2 diabetes, or lowering the risk of cardiovascular diseases

It inhibits GPX4, leading to tumor-specific ferroptosis, and TA is used to chemically reduce Fe 3+ to Fe 2+ and continuously supply Fe 2+ to maintain the iron redox cycle and maintain the Fenton reaction [201]