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However, not all patients respond effectively to GLP-1R monoagonists, and higher doses aimed at increasing efficacy result in adverse gastrointestinal effects

15: 100181 Karagounis L, Hawley J

For Zarghami, the early bliss of no longer thinking about or desiring food was soon replaced by concern about not being able to eat even tiny amounts like one eighth of a normal portion of scrambled eggs

Patients were excluded if they had a prescription fill within 60 days after the date of discontinuation or if the GLP-1 RA indication (AOM or ADM) could not be determined

This response occurs because Semaglutide GLP-1 acts on areas of the brain that help regulate hunger and satiety