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A tendency toward increased skin elasticity was observed in GSH and GSSG compared with placebo. Several randomized controlled trials also showed some evidence that GSH can act as a skin-whitening agent to some parts of the body or to certain age groups

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Liu XM, Kim KE, Kim KC, Nguyen XC, Han HJ, Jung MS, Kim HS, Kim SH, Park HC, Yun DJ, Chung WS: Cadmium activates Arabidopsis MPK3 and MPK6 via accumulation of reactive oxygen species

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Fasting administration allows glutathione to transit the stomach quickly and reach the duodenum where neutral pH and GGT enzyme activity facilitate absorption