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303 MiR-296-3p is negatively regulated by nicotine and directly targets MK2-induced Ras/Braf/ERK/Mek/c-Myc or PI3K/AKT/c-Myc signaling to suppress NPC cell proliferation, metastasis and chemotherapy resistance to DDP treatment

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Also, we discovered that lower SIRT1 levels hastened primordial follicle loss and follicular dormancy, which impacted the destiny of primordial follicles, and increased oxidative stress and harm to DNA, resulting in mitochondrial malfunction

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