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GLP-1 receptor agonists have entered the cultural bloodstream as forcefully as any medication in recent memory with more than one in eight Americans now reporting having used one, and TikTok hosting over 384,500 posts tagged #Ozempic as of early 2025

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It belongs to a class of medications called glucagon-like peptide-1 (GLP-1) receptor agonists, which were originally developed for type 2 diabetes management but have demonstrated significant efficacy in promoting weight loss

In one of the studies, patients with a mean baseline body mass index (BMI) of 35.3 kg/m and an average HbA1c of 8.3% were randomized to receive varying doses of GLP-3 (ranging from 1 mg to 12 mg) or placebo over a 36-week study period