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Studies of chondrocyte cultures suggest that it promotes proteoglycan and type II collagen synthesis, which has driven exploration of potential utility in joint and cartilage repair models

E-Posters - DIAGNOSIS / ETIOLOGY 04.00 - DIAGNOSIS / ETIOLOGY - 04.06 - CARDIOEMBOLISM & HEART-BRAIN INTERACTIONS P2339 - ESOC25-455 UNSUPERVISED CLUSTER ANALYSIS OF TRANSTHORACIC ECHOCARDIOGRAPHY PARAMETERS REVEALS DISTINCT PHENOTYPES IN ACUTE ISCHEMIC STROKE PATIENTS RECEIVING INTRAVENOUS THROMBOLYSIS AND ASSOCIATES WITH CLINICAL OUTCOMES Yue Ting Tang 1 , Aloysius Leow 2 , Chun En Yau 2 , Leonard Yeo 2,3 , Ching Hui Sia 2 , Benjamin Tan 2,3 1 Department of Geriatric Medicine, Khoo Teck Puat Hospital, National Healthcare Group, Singapore, Singapore, 2 Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore, 3 Division of Neurology, Department of Medicine, National University Hospital, Singapore, Singapore Background and Aims: Transthoracic echocardiography (TTE) performed during acute ischemic stroke (AIS) provides insights into heart-brain interactions

Mechanistic insight into the allosteric activation of a ubiquitin-conjugating enzyme by RING-type ubiquitin ligases

Ligand binding to the GIP receptor activates Gas, which in turn activates adenylate cyclase, resulting in the production of cAMP, in accordance with GLP- 1 receptor activation

Hakan Sarikaya: nothing to disclose