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Description

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In cell and animal models, amino acid metabolism not only provides substrates for energy production and biosynthesis, but also regulates the differentiation of macrophages toward M1 or M2 phenotypes by modulating signaling pathways such as STAT1, mechanistic target of rapamycin (mTOR), and NF-B, as well as by affecting epigenetic regulation (83)

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J Pineal Res 48:239250 Kim SY, Koo JE, Song MR, Lee JY (2013) Retinol suppresses the activation of toll-like receptors in MyD88- and STAT1-independent manners

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