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This observation ultimately led to the approval of higher-dose formulations of liraglutide (Saxenda) and semaglutide (Wegovy) specifically for sustained weight management, formally repositioning GLP-1 medications as obesity treatments rather than solely diabetes medications

Naltrexone is designed for moderation

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Regional Insights North America GLP-1 Receptor Agonist Market Trends North America dominates the GLP-1 receptor agonist market with a 41.8% share in 2025 , driven by the high prevalence of diabetes and obesity, coupled with strong healthcare infrastructure and widespread insurance coverage

While several multisociety statements have been published recently, the recommendations vary significantly in terms of medication management and preoperative fasting protocols for these patients