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[PubMed: 12072393] 58

KidneyDisease: Improving Global Outcomes (KDIGO) CKD Work Group

Its a key component of the electron transport chain, which is essential to creating adenosine triphosphate (ATP) fuel for your cells

Another analysis of 12 studies found that people who took alpha-lipoic acid lost an average of 2.8 pounds (1.27 kg) more than those taking a placebo over an average of 23 weeks ( In short, it seems that alpha-lipoic acid has just a slight effect on weight loss in humans

These factors collectively suggest that the conclusions, while robust, should be interpreted with caution in clinical decision-making