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Results: We included a total of 735 rtPA treated patients (53% males, mean age 67.7 years)
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Despite being a predominantly nuclear protein, several studies have indicated that during elevated ROS that ATM may translocate through the nuclear membrane to interact with cytosolic proteins localised in the peroxisome, mitochondria and microsome 52,53,54
AMGs are known to facilitate suppression of termination (at UGA or other stop codons) by altering proof-reading on ribosomes (246)
This may continue for several weeks or even months, as neurological recovery is often slower and more variable than haematological response
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