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Figure 2 GRP78-specific antibodies were found in up to 63% of RA patients, 7% of patients with other rheumatoid diseases, and only 1% of healthy controls (56)

These models have been widely used for studying angiogenesis and mechanisms behind shear stress-induced vascularization outside the context of ECD, but are also more focused on tumor angiogenesis [260, 261]

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Theme 3: Visible Filth and Physical Maintenance Failures Despite the industry's focus on high-tech validation, several warning letters from 2025 reveal shocking lapses in basic hygiene and maintenance