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Endogenous and exogenous reactive oxygen species, such as superoxide anion, hydroxyl radical, hypohalite radical, and hydrogen peroxide, and reactive nitrogen species, such as nitric oxide, peroxynitrite, and nitrite, play a major role in the airway inflammation and are determinants of asthma severity

PLoS Med 3: e102

In addition, a clinical study reported that NIN administration may be useful for treating NAFLD by modulating energy balance, glucose and lipid metabolism, oxidative stress, and inflammation through different mechanisms (Naeini et al., 2021)

Glutathione S -transferasesa review

Acute liver graft rejection after ipilimumab therapy