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at higher doses they can cause diarrhea that flushes magnesium out rather than repleting it

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Glucagon-like peptide-1 (GLP-1) stimulates insulin secretion from pancreatic -cells in hyperglycemic conditions but is cleaved by dipeptidyl peptidase-4 (DPP-4), an adipokine released in excessive amounts by adipose tissue in patients with obesity [85, 86]

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