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This is characterized by increased crypt depth, intact epithelial cell morphology, a higher relative density of goblet cells, and enhanced uniformity and richness of Prevotellaceae NK3B31 and Ruminococcus in the gut microbiota (Ma et al., 2023)

(00:22:10) Setting the psychological and mental landscape for why are we willing to do the painful things to, to actually make this be part of the practice is, is really the core foundation

The most significant clinical data for retatrutide to date comes from a Phase 2 randomised controlled trial published in The New England Journal of Medicine in 2023

When paired with GLP-1like in dual agonists such as tirzepatide and the triple agonist retatrutideit becomes a powerful driver of weight loss, improved glucose control, and insulin sensitivity