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.10.1007/s00125-023-05929-0 [DOI] [PMC free article] [PubMed] [Google Scholar] Associated Data This section collects any data citations, data availability statements, or supplementary materials included in this article

As GLP-1s have moved towards weekly dosing, users are less likely to experience the desensitisation that comes from repeated exposure

Overexpression efficiency was detected by Western blotting (Supplementary Fig

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When combining these medications, be alert for: Excessive nausea or gastrointestinal distress that affects daily functioning or medication adherence Significant mood changes, increased anxiety, agitation, or symptoms of mania Unusual fatigue or changes in sleep patterns Signs of dehydration, particularly if experiencing vomiting or diarrhoea Contraindications and Cautions: Wegovy is contraindicated in pregnancy and should be discontinued at least 2 months before a planned pregnancy due to its long half-life