CHAC1 activity is linked to cancer progression, influencing redox balance, cancer cell survival, proliferation, and therapy response
It notes these medications were originally developed for type 2 diabetes and have shown cardiovascular benefits independent of weight loss
Hu WM, Zhang J, Sun SX, Xi SY, Chen ZJ, Jiang XB, Lin FH, Chen ZH, Chen YS, Wang J, et al
Glycemic control, weight management, cardiovascular safety, and cost-effectiveness of semaglutide for patients with type 2 diabetes mellitus: a rapid review and meta-analysis of real-world studies
6) Berberine may have extra beneficial effects on diabetic cardiovascular complications due to its cholesterol-lowering, anti-arrhythmias and nitric oxide (NO) inducing properties