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However, the importance of protein-level assessments, especially for deciphering the phenotypic effects of LMNA variants, emerged as a critical oversight

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ACC1 is the physiological converter of acetyl-CoA to malonyl-CoA, and the latter is the Spark for fatty acid production, as well as a blocker to carnitine palmitoyl transferase 1 (CPT1) [67, 69]

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