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When only the N-terminal G6PD5.4 domain was used, there was still a tendency for the reporter fusions to accumulate in focal ER sites

However, there is also a possibility that some of the effect may be independent of GLP-1, because DPP-4 inhibition still reduced -cell apoptosis in human islets cultured in the presence of exendin 9-39 (99), suggesting that other mediators might be involved, but it was also suggested that an anti-inflammatory action could have played a role (99)

If another medication must also be taken in the morning, your prescriber can help decide which one takes priority and how to time them safely