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The prevalence and phenotypic features of polycystic ovary syndrome: A systematic review and meta-analysis

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In most cases, symptoms are temporary and lessen as the body adapts

Early-phase clinical trial data, including results from a Phase 2 trial published in The New England Journal of Medicine in 2023, demonstrated substantial weight reductions in some participants exceeding 20% of body weight over 48 weeks alongside a broadly manageable short-term adverse effect profile