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For differentiating subjects with schizophrenia from controls at baseline, a combination of seven acyl-carnitines, including C4OH (C3DC), C8, C10:1, C12, C14:1OH, C14:2, and C16:1, provided the best classification performance with the AUC = 0.926 (95% CI: 0.9010.952)

Tolerability and Safety Questions Both candidates are likely to be judged partly on gastrointestinal tolerability: nausea, vomiting, diarrhea, constipation, dose escalation, and discontinuation due to adverse events