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Outcome of biliopancreatic diversion in subjects with prader-willi syndrome

This was a dedicated CV outcome trial, enrolling high-risk overweight and obese patients (without DM type 2) and showed an early reduction in all-cause mortality and a 20 per cent RR reduction in hard end clinical endpoints

The SURPASS-CVOT trial (NCT04255433) will assess the cardiovascular safety of tirzepatide compared to dulaglutide in people with T2D and established atherosclerotic disease [111]