10.1097/sla.0b013e3181ae32e3 Ann
C12 stimulate GLP-1 secretion, whereas C10 do not.56 Regarding the relationship between GLP-1 and macronutrients in controlling food intake, a study showed that maintenance on high-fat diet in rats impairs GLP-1s ability to reduce food intake, contributing to overconsumption of high-fat foods.80 Gut hormones and obesity The epidemic obesity is fastly becoming one of the leading causes of mortality and morbidity worldwide
Buse JB, Bode BW, Mertens A, Cho YM, Christiansen E, Hertz CL, Nielsen MA, Pieber TR
You can lose weight that way, but if you go from diet back to your usual food intake, you'll regain not only the original weight, but you'll overshoot and gain some additional weight
He said future research should assess the economic impact of combined SGLT2 and GLP-1 therapy in different settings