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Some create overlapping effects that waste resources

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Additionally, these medications enhance glucose-dependent insulin secretion from pancreatic beta cells whilst suppressing inappropriate glucagon release, thereby improving glycaemic control in individuals with type 2 diabetes

All animal experiments were carried out following the guidelines of the Institutional Animal Care Committee of Southern Medical University and national animal experimental ethics standards

Then the SELECT cardiovascular outcomes trial added a 20% reduction in major adverse cardiovascular events in overweight and obese patients with established heart disease independent of diabetes status, and partially independent of the weight loss itself