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Berlin H, Berlin R, Brante G (1968) Oral treatment of pernicious anemia with high doses of vitamin B12 without intrinsic factor

Cobalamin should be supplemented whenever serum cobalamin concentration is in the low normal range (i.e., less than approximately 400 ng/L) in both dogs and cats

Thiamine (B) is generally recognized as safe in pregnancy and is in fact critical to prevent deficiency in pregnant patients with prolonged vomiting

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Interactions with Medications: Vitamin B12 has the potential to interact with certain medications, including diabetic prescriptions, metformin, proton pump inhibitors, antagonists and antibiotics