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Because of the above evidence for selection of potential revertants and of pGSH1 upregulation upon 5-FOA treatment (implying a generic response), it was concluded that URA3 is not a suitable counter-selectable marker in this system for selection of phenotypically high-GSH producers

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Consistent with murine ILC2s, melatonin increased human ILC2 expression of GCLC, the rate-limiting enzyme in glutathione synthesis, as well as NRF2 ( Figures 8B, C )

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