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Reports by Wileman and colleagues suggest a potential link between GLP-1s and renal complications, such as acute kidney injury, but these are rare and thought to result from dehydration caused by GI side effects

Translating preclinical findings into effective patient treatments will necessitate further advancements in delivery methods and long-term efficacy

Another issue with protease inhibitors is pharmacological interactions with co-administered glucose-lowering drugs

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Patients with post-thrombotic syndrome develop symptoms like pain, aching, and itching in the legs, skin discoloration, swelling, and in severe cases, scaling or ulceration in the affected area