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Funding This work was supported by National Natural Science Foundation of China (32070930, 82160497), Key R & D Plan Project of Ningxia Autonomous Region (2020BFG02012), Natural Science Foundation of Ningxia (2022AAC02034, 2020AAC03154), Science Research Project of Ningxias Colleges (NGY2020043), Science and Technology Project of Jiangsu Market Supervision Administration (KJ207561), First-Class Discipline Construction Founded Project of Ningxia Medical University and the School of Clinical Medicine (NXYLXK2017A05), Zhenjiang Social Development Project (SH2020036), Ningxia Innovation And Entrepreneurship Projects for Returnees, Ningxia Youth Top Talent Training Project and Light of the West Talent Training Programme of the Chinese Academy of Sciences