Hormone replacement therapy restores healthy levels, easing uncomfortable symptoms and boosting energy
Although the findings were promising, the studys credibility is tempered by its small sample size (n = 10), short duration of treatment, and the absence of detailed dietary intake data during the trial period [112]
doi: 10.1016/j.diabres.2018.10.013 10 HoganAETobinAMAhernTCorriganMAGaoatsweGJacksonRet al
According to a subgroup analysis of Korean patients with newly diagnosed T2DM among the VERIFY trial participants, early combination treatment significantly and consistently improved long-term glycemic durability compared to monotherapy with metformin [43]
Specifically, after 56 weeks, weight reductions were 10.6% for the 15/92 mg dose, 8.4% for the 7.5/46 mg dose, and 5.1% for the 3.75/23 mg dose, with all comparisons yielding p-values less than 0.0001