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The PV1-BSOr mutants were plaque purified and the RNAs were subjected to RT-PCR and sequence analysis

Patented Medicine Prices Review Board (PMPRB) Federal agency that reviews and regulates the prices of patented medicines sold in Canada, including GLP-1 receptor agonists like semaglutide

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Diabetes (2009) 58:105866.10.2337/db08-1237 187 LanHLinHVWangCFWrightMJXuSKangLet alAgonists at GPR119 mediate secretion of GLP-1 from mouse enteroendocrine cells through glucose-independent pathways

Heart rate elevation and autonomic effects One of the most consistent physiological effects observed with GLP-1 RAs is a modest, dose-dependent increase in heart rate, typically ranging from 2 to 5 beats per minute